United have never had so many points as they have at this stage of a season - with 65 from just 26 games and they now have a 12 point gap over title holders, Manchester City.
City fans will cling onto the hope that they can mount a late surge as they did last season, but then they clawed back an 8 point gap from March.
But City look some way off the form that lifted the title, with too many stars performing under par. Joe Hart had a nightmare at Southampton on Saturday, Carlos Tevez was missing for family reasons, and Aguero is struggling to find the net.
United seem to have enough strength in depth to field two teams capable of winning the title, and Ryan Giggs - starting against Everton scored United's opener in a 2-0 victory. It was the 23rd season running that Giggs has scored a Premier League goal - a record in its own rights. Robin Van Persie - who else - added a second.
It was revenge of sorts for Alex Ferguson,as he has pinpointed the 4-4 draw with Everton last April, when United squandered a two goal lead in the last 8 minutes, as the moment they lost the title to City.
But the real irony is the fact that Ferguson made fewer changes than many thought. He admitted after the game that City's defeat on saturday had made him re-think things as a potental 12 point gap in the table was up for grabs. He decided against resting his stars with the mid-week Champions League game looming.
Given that Ferguson had criticised the Premier League all week for making United play on Sunday ahead of the big European clash, the irony is that he has now benefitetd from the situation as he was able to see how City had done and alter his game plan accordingly.
The bigger concern though for the authorities is the impact generally if the title is almost a foregone conclusion with three months of the season left to play.