Two massive derbies matches were made when the sides were drawn for the Third Round of The Capital One Cup.
Last year's beaten finalist Spurs will face their arch North London rivals Arsenal in the next round, which will be both sides' first game in the competition, having had a buy through the opening rounds due to European football commitments.
There is also a feisty Second City derby on the cards, as Championship side Birmingham take on Aston Villa, who needed extra time to overcome Notts County 5-3 in the end.
Of the other Premier League sides entering at this stage, Manchester United and Chelsea face lower league opposition in Ipswich and Walsall respectively, whilst Liverpool face Carlisle, who overcame QPR last night.
There are three other all Premier League ties, as Leicester host West Ham, Norwich take on West Brom, and Manchester City travel to Sunderland.
The only Premier League side not in the Third Round is Watford, who made eleven changes to their side and were dispatched by Preston 1-0, who will now face another Premier League side in Bournemouth.
The Full draw is below:
Middlesbrough v Wolves
Norwich v West Brom
Hull City v Swansea
Leicester City v West Ham
Aston Villa v Birmingham City
Tottenham v Arsenal
Manchester United v Ipswich Town
Liverpool v Carlisle
Crystal Palace v Charlton
Fulham v Stoke City
Sunderland v Manchester City
Newcastle v Sheffield Wednesday
Reading v Barnsley or Everton
Preston v Bournemouth
Walsall v Chelsea
MK Dons v Southampton
Ties to be played in the week commencing September 21