The Seasiders' friendly against Lancaster on 11 July was abandoned after some fans invaded the pitch in protest against chairman Karl Oyston.
The League One club say they are "extremely disappointed" their match against Morecambe has been called off.
Blackpool were relegated from the Championship last season.
The protest at Lancaster was the latest in a number of disputes between fans and the Oyston family over their running of the club.
Blackpool's last Championship game of the season - against Huddersfield - was abandoned on 48 minutes after supporters invaded the pitch.