Roy Hodgson named his England side, with West Brom striker Saido Berahino in line to receive his first senior cap.
Hodgson also included West Ham's Stewart Downing for his first call up in over two years, as well as recalling Manchester United's Michael Carrick and Arsenal's Theo Walcott.
Carrick has only recently returned to action following an injury in the summer, whilst Walcott has only made one substitute appearance since suffering a long term injury in January.
Berahino is the leading English scorer in the Premier League this season, with seven goals from his ten games, whilst Stewart Downing is second only to Chelsea's Cesc Fabregas for the number of chances created and assists made.
The trio are part of nearly a third of the squad who weren't in the World Cup Squad in Brazil, with stalwarts Steven Gerrard and Frank Lampard having since retired, and Daniel Sturridge omitted again through injury.
England face Slovenia at Wembley on 15 November, before a friendly match against fierce rivals Scotland on November 18th. Captain Wayne Rooney could win his 100th cap for his country during the international break.
The full squad is as follows:
Goalkeepers: Fraser Forster, Ben Foster and Joe Hart
Defenders: Leighton Baines, Gary Cahill, Calum Chambers, Nathaniel Clyne, Kieran Gibbs, Phil Jagielka, Luke Shaw and Chris Smalling.
Midfielders: Ross Barkley, Michael Carrick, Stewart Downing, Jordan Henderson, Adam Lallana, James Milner, Alex Oxlade-Chamberlain, Raheem Sterling, Andros Townsend, Jack Wilshere and Theo Walcott.
Forwards: Rickie Lambert, Wayne Rooney, Daniel Welbeck and Saido Berahino.